Exercise May Slow Biological Aging in Breast Cancer Survivors, Randomized Trial Analysis Suggests
HealthOncodaily

Exercise May Slow Biological Aging in Breast Cancer Survivors, Randomized Trial Analysis Suggests

A 12-month exercise program was linked to slower biological aging and better brain function in breast cancer survivors, a new study found.

A randomized trial found that a 12-month exercise intervention was associated with slower epigenetic aging and cognitive benefits in breast cancer survivors.

The Long Sip
What happened

A secondary analysis of the randomised I Can! trial found that a year-long exercise program slowed epigenetic aging in breast cancer survivors.

The detail

The study, published in the Journal of the National Cancer Institute, also found faster epigenetic aging was linked to worse attention and cognition after treatment.

What it means

Researchers say the findings suggest physical activity may influence biological aging processes, though they stress it does not literally make survivors younger.

For you

The study found the exercise program was delivered remotely over 12 months, so ask your oncology team whether a similar program suits your situation.

Full story at Oncodaily

What readers are saying

nancy50
The link between epigenetic aging and cognitive health is significant, especially since the study specifically mentions changes in the BDNF pathways. It is encouraging to see that even a modest increase in moderate-to-vigorous activity, moving from 12 to 22 minutes a day, can produce measurable biological differences compared to the wellness control group.
PopDi
Does the study mention if these biological changes lasted once the 12-month coaching and Fitbit support ended?
OldLinda
It is interesting that the benefit came from just an extra ten minutes of activity a day rather than hours at the gym. We need to focus more on these DNA methylation markers because they provide a concrete way to measure how oncology treatments like chemotherapy actually accelerate the physical aging process in women.
PalmwoodsRen
The BDNF pathways in the DNA methylation changes really stand out. That connection to brain health could explain why slower epigenetic aging also tied to better attention and cognition in the survivors.
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