HealthPhys.orgNew nanoparticle drug-delivery method may improve treatment for endometriosis
US researchers have developed a nanoparticle drug treatment that reduced endometriosis symptoms after a single dose in early mouse testing, raising hopes for a future human therapy.
Researchers have engineered a drug treatment that shows rapid effectiveness against endometriosis in early testing, laying the foundation for a potential therapy for an incurable, chronic disease that affects 1 in 10 women. The targeted nanotherapy, developed by a team of scientists at Washington State University, reduced endometriosis symptoms and disease progression after a single dose in a mouse model.
Scientists at Washington State University engineered a nanoparticle that delivers an existing drug directly to endometriosis lesions, reducing symptoms after a single dose in mouse testing.
The treatment uses niclosamide, a drug already approved to treat intestinal tapeworms, carried by a tiny nanoparticle that targets a specific immune cell linked to the disease.
Endometriosis affects roughly 190 million women worldwide and has no cure, and the researchers say they hope to eventually test the approach in humans.
The researchers at Washington State University hope to eventually test the treatment in humans, so women with endometriosis may want to ask their GP about emerging therapies as trials progress.
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