This Dangerous Fungus Has Become Resistant to Every Major Antifungal Drug We Have… Twice

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KoreanAusHyun
The stop-gain mutation in the FUR1 gene is what knocked out flucytosine resistance on top of the ERG11, CDR1 and FKS1 changes. That combination makes the isolate truly pan-drug-resistant and shows the fungus can evolve multiple mechanisms at once in a single patient.
normaw44
How did the 28 year old woman in Nairobi pick up this strain after elective surgery?
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