
Scientists transplant lab-grown human brain tissue into mice
Stanford scientists have transplanted lab-grown human brain tissue into mice, potentially speeding up research into autism, epilepsy and schizophrenia.
Scientists have transplanted laboratory-grown human brain tissue into bioengineered mice in what they call an important advance for studying human brain development that may speed research into the causes and mechanisms of devastating disorders such as profound autism, epilepsy, cerebral palsy and schizophrenia. The researchers said the human tissue replicated…
Scientists transplanted laboratory-grown human brain organoids into bioengineered mice, creating a new way to study human brain development, the journal Nature reported.
The mice were engineered to lack most of their own cerebral cortex, giving the transplanted human tissue room to grow and form functional neural networks.
Researchers say the advance could speed up understanding of conditions like autism, epilepsy and schizophrenia, since living human brain tissue is otherwise inaccessible for ethical reasons.
The researchers say this method could help test whether potential treatments can prevent or correct disease-related changes in human brain development, which may eventually benefit patients.
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