HealthCancerNetworkRadiation Omission in Favorable Breast Cancer Hinges on Endocrine Adherence
A long-term trial found that carefully selected postmenopausal women with low-risk breast cancer may safely skip radiation, but only if they can stick with hormone therapy for five years.
Leah Katz, MD, MPH, discusses long-term IDEA trial data on omitting radiation and why endocrine therapy tolerance matters in this decision.
Long-term data from the IDEA trial showed postmenopausal women with low-risk breast cancer had a 94% recurrence-free rate at 8 years without radiation.
The trial enrolled 200 women aged 50 to 69 with stage I, estrogen receptor-positive, HER2-negative cancer who took endocrine therapy alone after breast-conserving surgery.
Radiation omission is a real option for some women, but the oncologist cautioned that endocrine therapy side effects can be severe and the window to switch to radiation closes quickly.
If you or someone you know has early-stage, hormone-positive breast cancer, ask your oncologist whether your recurrence score and tolerance for endocrine therapy make radiation omission worth…
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